Saturday, October 1, 2011

Chimerism


Chimera is an individual cells derived from more than one ovum is fertilized. Chimerism must be distinguished from mosaicism, namely the formation of 2 or more derivative cells with different chromosomal compositions originating from the same zygote due process of nondisjunction during meiotic division. One possible mechanism for the establishment of chimerism is the transfer of genetic material from a fetus of non-identical twin to the other fetus via vascular anastomosis chorion. The cells are transferred shall not be destroyed, because the transfer occurs before the fetal immune system is mature and fetal recipients become tolerant to donor tissue antigens are different. Blood Chimerism in mind when deciding on the most common blood type is the discovery of cells with 2 different blood type at one person.

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