Sunday, March 13, 2011

Herpes Zoster (Shingles)


Etiology
Herpes zoster is an acute skin inflammation, has peculiar properties of vesicles arranged in groups along the skin sensory innervation in accordance dermatomes. Herpes zoster is caused by the varicella-zoster virus (VZV) that are localized. As a continuation of the attacks of varicella, the virus that remains in the dorsal root ganglia of the posterior edge of the nervous system and cranial ganglion silent and remain dormant until some stimulus causes reactivation causing shingles. Sometimes this virus also attacks the anterior ganglion, thus giving the symptoms of motor disorders. Middle age and old age are most often affected, although it can sometimes arise during childhood. This condition is more common in people with immunosuppression.


Clinical Overview
Herpes zoster is usually about one dermatome, where the most together usually is on the chest and abdomen. Usually there is neuralgia few days before or in conjunction with skin disorders. Sometimes before a skin disorder arising preceded by fever, headache, and malaise. Skin disorder is the early form of erythema and then developed into groups of papules and vesicles that rapidly unilateral enlarged and fused to form the bull. Vesicle contents at first clear, after several days became cloudy and can also be mixed with blood. If absorption occurs, vesicles and the bull will be crusting.
The situation is most disturbing is the presence of herpes zoster pain that is persistent even though the lesion is gone (postherpetic neuralgia).


Differential Diagnosis
Herpes simplex, Varicella, Allergic contact dermatitis.


Prognosis
In young people and children is generally good.

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